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FreeO2 automated oxygen therapy

Automated oxygen titration and weaning

A new and innovative technology designed to automate oxygen titration and weaning to regulate SpO2 levels.

About Product

Regardless of a patient’s age (infant, child or adult), their oxygen needs and response times, FreeO2 automatically adjusts the oxygen flow rate required to maintain target oxygenation set by the clinician, until the patient is fully weaned.

FreeO2 operates on a closed loop and continuously adjusts the flow rate administered between 0 and 20 l/min (with or without humidification) based on blood oxygen saturation (SpO2).

Patients are therefore treated according to their needs, which reduces the risks of complications relating to hypoxia and hyperoxia. This means healthcare staff are also able to implement all applicable clinical recommendations without difficulty.

UOI Units: Single

UOI: 1

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About Free02

A versatile, simple and user-friendly tool

Intended for all medical departments in hospitals

FreeO2 is suitable for all patients, from infant to adults, breathing independently and requiring oxygen therapy. It offers a simple and user-friendly touch screen interface, enabling all healthcare staff to master the system quickly. It takes just a few clicks to start, pause or resume treatment and to access all monitoring settings.

Oxygen Therapy Setting


Overview in Graphical Format


Cardio-Respiratory Monitoring


Continuous monitoring of oxygen therapy to ensure better oversight of patients’ progress

FreeO2  uses an oximeter worn continuously by the patient. The oximeter makes it possible to monitor and record conventional cardio-respiratory parameters and, following analysis of the plethysmographic signal, to extract other physiological parameters such as the respiratory rate. Continuous recording of these parameters, can be shown in graphical format and or up to 72 hours, offers access, to essential information at a patients bedside for decision-making, assessing and evaluating any necessary changes in the respiratory support provided.

Medico-Economic Benefit

at every stage of treatment

FreeO2  has been devised and developed by clinicians to combat the dangers of oxygen toxicity1-8. It removes the difficulties previously experienced by healthcare staff to  correctly manage patients receiving oxygen therapy in routine clinical situations. Before its launch, FreeO2  was involved a number of studies and clinical trials with more than 500 patients.

% of time spent at target Sp02

  • Safer and more clinically effective oxygen therapy

  • Far fewer complications relating to hypoxia and hyperoxia

  • Significant reductions in the time spent in hospital and the costs of care.

To care for patients with acute respiratory distress in emergency departments, FreeO2 makes it possible to treat people more effectively (assessed according to the time spent at the target SpO2). This limits complications relating to hypoxia and hyperoxia, it weans patients with certain conditions more quickly and avoids transfers to intensive care. In addition, the data in one study9 points to a reduction in the workload of healthcare staff and greater compliance with clinical protocols.

Cost per patient at 180 days (CAD)


When FreeO2 was tested with patients admitted to hospital for an exacerbation of COPD10, a key benefit was the ability to remotely monitor the automated titration and weaning from the nurses’ station. Hospital stays were also reduced by around 30% (6.7 days compared with 9.5 days).

In a study of COPD patients11 undergoing walking endurance exercises, the use of FreeO2 resulted in more effective oxygenation and an effort endurance time significantly greater than that of the control group. Even when FreeO2 delivered higher oxygen flow rates no cases of hypercapnia occurred as target SpO2 adjustments prevented the onset of hyperoxia.

Duration of hospital stays (days)


Walking endurance


Clinical studies

  1. O’Driscoll BR1, Howard LS, Davison AG; British Thoracic Society. BTS guideline for emergency oxygen use in adult patients.
  2. Cameron L1, Pilcher J, Weatherall M, Beasley R, Perrin K. The risk of serious adverse outcomes associated with hypoxaemia and hyperoxaemia in acute exacerbations of COPD. Postgrad Med J. 2012 Dec;88(1046):684-9.
  3. Hale KE, Gavin C, O’Driscoll BR. Audit of oxygen use in emergency ambulances and in a hospital emergency department. Emergency medicine journal : EMJ. 2008;25(11):773-776.
  4. Ringbaek TJ1, Terkelsen J1, Lange P2. Outcomes of acute exacerbations in COPD in relation to prehospital oxygen therapy.Eur Clin Respir J. 2015 May 11;2. doi: 10.3402/ecrj. v2.27283. eCollection 2015.
  5. McNulty PH, King N, Scott S, et al. Effects of supplemental oxygen administration on coronary blood flow in patients undergoing cardiac catheterization. American journal of physiology. Heart and circulatory physiology. 2005;288(3):H1057-1062.
  6. Stub D, Smith K, Bernard S, Nehme Z, Stephenson M, Bray JE, Cameron P, Barger B, Ellims AH, Taylor AJ, Meredith IT, Kaye DM; AVOID Investigators..Air Versus Oxygen in ST-SegmentElevation Myocardial Infarc-tion. Circulation. 2015 Jun 16; 131(24):2143-50.
  7. Nehme Z1, Stub D2, Bernard S3, Stephenson M4, Bray JE5, Cameron P5, Meredith IT6, Barger B4, Ellims AH7, Taylor AJ7, Kaye DM8, Smith K9; AVOID Investigators. Effect of supplemental oxygen exposure on myocardial injury in ST-elevation myocardial infarction. Heart. 2016 Mar;102(6):444-51.
  8. Girardis M, Busani S, Damiani E, Donati A, Rinaldi L, Marudi A, Morelli A, Antonelli M, Singer M. Effect of Conservative vs Conventional Oxygen Therapy on Mortality Among Patients in an Intensive Care Unit: The Oxygen-ICU Randomized Clinical Trial. JAMA. 2016.
  9. L’Her E, Dias P, Gouillou M, et al. Automatic versus manual oxygen administration in the emergency department. Eur Respir J 2017; 50: 1602552 [https://doi.org/10.1183/13993003.02552-2016].
  10. Lellouche F, Bouchard P et al. Automated oxygen titration and weaning with FreeO2 in patients with acute exacerbation of COPD: a pilot randomized trial. Doverpress 24 August 2016 Volume 2016:11(1) Pages 1983—1990.
  11. I.Viodtzev, E LHer, C Yankoff, A Grangier, G Vottero, V Mayer, D Veale, F Maltais,F Lellouche, JL Pépin. Automatically adjusted oxygen flow rates to maintain stable oxygen saturations during exercise in O2 - dependent and hypercapnic COPD patients ERS 2017 meeting: Best abstracts in exercise capacity and testing in chronic lung disease September 4th 2016 from 14:45 to 16:45 in Room ICC Captial Suite 7.

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